Autism Genetic Resource Exchange | Autism PDD

Share

Genomics Initiative

There is no doubt that traditional academic methods will find the genes for autism and these genes will lead us to biological treatments. The issue is when.

Cure Autism Now proposes to lead the charge by aggressive and focused grant making and contract work which will include fine mapping, SNP mapping, micro array work and the continued development and expansion of a central data repository for genomics information.

In an effort to facilitate the progress of discovery, Cure Autism Now founded and fully funds the Autism Genetic Resource Exchange (AGRE), an open gene bank with a large collection of immortalized cell lines and DNA samples from families with more than one child with autism.  These samples and the accompanying clinical data are available to the entire scientific community.

The establishment of the AGRE has created an invaluable resource for the scientific community.  When AGRE began, six researchers were studying the genetics of autism - today there are over 300. 

In 2003 the Autism Genetic Resource Exchange will make the DNA samples of over 400 multiplex families available for study to all scientists and pharmaceuticals, thus making it the largest autism collections in the world and the only one that is open to the entire scientific community.

Our goal is to identify several of the genes involved in autism within the next three years.

Does your family have two or more children diagnosed with autism, PDD or Asperger's syndrome?

The Autism Genetic Resource Exchange (AGRE) advances genetic research in autism by obtaining blood samples and clinical data from families that have two or more children diagnosed with autism, PDD or Asperger's syndrome. Find out how to participate!

http://www.cureautismnow.org/research/initiative/3416.jsp

Tell us about your family. Click here to complete the secure online Family Contact Form, or click to print the Family Contact Form.

AGRE's Key Objectives: The Autism Genetic Resource Exchange (AGRE) was created by Cure Autism Now to advance autism research in autism spectrum disorders. Read more.

AGRE Participation: AGRE requires families to complete a series of activity steps involving three visits to the family's home-the diagnostic assessment, the family blood draw and a diagnostic physician visit. Find out more.

Research Updates: Over the last five years, the AGRE resource has contributed to new science publications, laying the groundwork for discovering causes, treatments and a cure for autism. Read updates.

To learn more, please visit AGRE's Frequently Asked Questions. If you still have questions, comments or concerns, feel free to contact the AGRE staff.

Browse the AGRE Family Newsletter: "Listening To You" (PDFs)

2005  |  2004  |  2003

MsSteelersFan38583.4912037037

http://www.cureautismnow.org/research/initiative/1513.jsp

Biomarkers Initiative

One of the biggest problems in autism is the lack of a biological test or marker for diagnosis. 

Cure Autism Now is very excited about two preliminary findings of potential biomarkers for autism resulting from CAN funding and/or the donation of the AGRE sample.  Researchers have identified an unusual protein in the urine of children with autism and some of their unaffected relatives.  In another recent finding a distinct lipid profile was seen strongly associated with 20 AGRE samples.  In 2003 we will put significant effort into replicating and confirming these results that could lead to a potential biomarker for autism.


Copyright Autism-PDD.net